Self-powered Integrated Microfluidic Blood Analysis System (SIMBAS) is a batteryless self-powered Microfluidic Biochip is that can diagnose to detect diseases such as HIV or tuberculosis in a matter of minutes. SIMBAS Microfluidic Biochip is a true lab-on-a-chip that revolutionizes global health care diagnostics. SIMBAS is a stand alone biochip that diagnoses diseases within 10 minutes without electricity, chemicals, or any other external tubing.

Microfluidic Blood Analysis System BiochipSIMBAS Microfluidic Biochip is developed by scientists from the UC Berkeley, Dublin City University in Ireland and Universidad de Valpara√≠so Chile. The SIMBAS biochip uses trenches patterned underneath microfluidic channels that are about the width of a human hair. When whole blood is dropped onto the chip’s inlets, the relatively heavy red and white blood cells settle down into the trenches, separating from the clear blood plasma. The blood moves through the chip in a process called degas-driven flow. For degas-driven flow, air molecules inside the porous polymeric device are removed by placing the device in a vacuum-sealed package. When the seal is broken, the device is brought to atmospheric conditions, and air molecules are reabsorbed into the device material. This generates a pressure difference, which drives the blood fluid flow in the chip.

“This is a very important development for global healthcare diagnostics,” said Luke Lee, UC Berkeley professor of bioengineering and co-director of the Berkeley Sensor and Actuator Center. “Field workers would be able to use this device to detect diseases such as HIV or tuberculosis in a matter of minutes. The fact that we reduced the complexity of the biochip and used plastic components makes it much easier to manufacture in high volume at low cost. Our goal is to address global health care needs with diagnostic devices that are functional, cheap and truly portable.”